22 August 2010
A recent retrospective analysis, the findings of which were published in the journal, Human Reproduction, reports that performing additional rounds of hybridization during fluorescence in situ hybridization (FISH) improves the accuracy of the technique in preimplantation genetic aneuploidy screening (PGS), thereby increasing the number of competent embryos available for transfer.
Posted in ART, Diagnostics, Genetics, IUI, IVF, PGD, TechnologyComments Off
22 August 2010
A new breakthrough study has reported the development of a simple, non-invasive, prenatal blood test based on the multiplex ligation-dependent probe amplification (MLPA) technique, which could help in the accurate detection of chromosomal aberrations in the developing fetus, and thereby avoid the risk of miscarriage associated with conventional invasive techniques such as chorionic villus sampling [...]
Posted in Diagnostics, Fertility, Genetics, Laboratory, PGD, Pregnancy, TechnologyComments Off
12 August 2010
A new breakthrough blood test that helps predict the approximate age at which a woman would attain menopause has been developed. The preliminary findings of this population-based cohort study were presented at the 26th annual meeting of the European Society of Human Reproduction and Embryology (ESHRE) held at Rome from 27th to 30th June 2010. [...]
Posted in Diagnostics, Endocrinology, Fertility, Fertility Preservation, Menopause, News, Technology0 Comments
06 August 2010
Several studies have established the effect of obesity (BMI >30 kg/m2) on female fertility as well as on ART treatment outcomes; however, the mechanism underlying the association is still obscure. Now, a recent study published in the journal Reproduction, sheds more light on the impact of obesity on the major reproductive mechanisms and infertility treatment. [...]
Posted in ART, Female Infertility, Guidelines, IVF, IVF Outcome, InfertilityComments Off
31 July 2010
Potential screening tools for early ovarian ageing include small antral follicle counts, anti-Müllerian hormone levels, abnormal autoimmune function, and number of CGG repeats on the fragile X mental retardation 1 (FMR1) gene. A recent preliminary prospective randomized controlled trial reiterates that 30 to 40 CGG trinucleotide repeats on FMR1 may serve as a predictor of [...]
Posted in ART, Endocrinology, Female Infertility, Fertility, Genetics, Infertility, Laboratory, TechnologyComments Off
22 July 2010
Crinone® vaginal gel, a natural progesterone supplementation approved by the U.S. FDA for women undergoing assisted reproduction, has better tolerability and comparable effectiveness to intramuscular progesterone (IMP) for luteal phase support during in vitro fertilization-embryo transfer (IVF-ET) cycles, according to the findings of a prospective randomized trial published in the online issue of the journal, [...]
Posted in ART, Drugs, Female Infertility, IVF Outcome, MiscarriageComments Off
16 July 2010
A team of researchers from the Newcastle University have developed a pioneering ‘three-person IVF’ technique, in which the fertilization procedure uses the nuclear DNA of the biological parents, and the mitochondrial DNA (mtDNA) from an oocyte donor. The technique, which facilitates exchange of DNA between two oocytes, could serve in preventing the transmission of mitochondrial [...]
Posted in ART, Donors, Embryology, Ethics, Genetics, Infertility, Laboratory, News, Stem Cells, Technology0 Comments
06 July 2010
Previous studies have correlated parental infertility or its treatment with childhood cancer. However, very few have investigated its impact on individual cancer subtypes. A recent case-controlled study published in the journal Human Reproduction reports that no significant relationship exists between parental infertility/infertility treatment and infant leukemia.
Posted in ART, Drugs, Female Infertility, Infertility, Male Infertility0 Comments
24 June 2010
A large prospective follow-up study has concluded that the long-term safety of ganirelix, a GnRH antagonist, with respect to neonatal outcomes and major malformation risk, is comparable to that of traditional GnRH agonists used in controlled ovarian stimulation (COS) cycles. The study findings have been published in the journal, Human Reproduction.
Posted in ART, Drugs, Genetics, IVF, IVF Outcome, InfertilityComments Off
20 June 2010
Mutations in the Deleted in Azoospermia-like (DAZL) gene, an autosomal homolog of the DAZ gene located on chromosome 3p24, have been linked to spermatogenic abnormalities. Now, a prospective study published in the journal, Reproductive BioMedicine Online, provides further credence to the probable involvement of DAZL in the regulation of sperm counts, motility, and possibly also [...]
Posted in ART, Genetics, Infertility, Male InfertilityComments Off
Added on 11 February 2010
Randomized Trial Reports Similar Live Birth Rates with Single and Double IUI
Resection May Improve Fertility and Clinical Outcomes in Infertile Women with Bowel Endometriosis
