19 January 2012
Obesity adversely affects the reproductive health of a woman as it is known to cause anovulation, menstrual irregularities, and infertility. However, the findings of various studies on the influence of BMI on controlled ovarian hyperstimulation factors, such as quantity of gonadotropin and days of stimulation required, oocyte quality/quantity, maximum level of estradiol, and success of [...]
Posted in ART, Female Infertility, Guidelines, IVF, IVF Outcome, Infertility, Miscarriage, PregnancyComments Off
14 December 2011
The psychological outcome of infertility on women has been extensively studied in the past; however, research on the effect of the diagnosis of azoospermia on men and their fertile spouses is lacking. Now, a recent study, touted to be the first to report the negative effect of infertility on the physical and psychological wellness of [...]
Posted in Endocrinology, Fertility, IVF, IVF Outcome, Infertility, Male InfertilityComments Off
04 December 2011
Dehydroepiandrosterone (DHEA) is considered to increase the chances of pregnancy in women with decreased ovarian reserve (DOR), and is frequently used in nearly over a third of IVF centers worldwide. Adding credence to the currently available level II and III evidences, a comprehensive review and meta-analysis has reported that DHEA supplementation improves pregnancy chances in [...]
Posted in Female Infertility, Fertility, IVF, IVF Outcome, Infertility, Menopause, Miscarriage, PregnancyComments Off
22 November 2011
Over the past two decades, ultrasound-guided transvaginal aspiration has emerged as the gold standard for oocyte retrieval in IVF. Pain experienced during the procedure is influenced by factors such as anxiety, type of analgesia, type and amount of additional IV analgesia, needle sharpness and diameter, pain threshold of the patient, and the doctor’s skills. A [...]
Posted in Equipments, Fertility, IVF, IVF Outcome, Laboratory, News, Pregnancy, TechnologyComments Off
13 November 2011
Endometrial receptivity plays a crucial role in embryo implantation and successful pregnancy; however, the key molecules or mechanisms associated with it are still unclear. Various methods used to identify biomarkers of endometrial receptivity include blood and uterine fluid analysis, endometrial ultrasonography, and biopsy examination. Now, in a genome-wide observational study, researchers have highlighted the potential [...]
Posted in ART, Endometrium, Female Infertility, Fertility, Genetics, IVF, IVF Outcome, Implantation, Infertility, TechnologyComments Off
05 November 2011
A single-center retrospective study on 2,450 infertile women has reaffirmed that the quality and quantity of whole embryos serve as the most vital independent predictors of cumulative IVF/ICSI outcomes. Furthermore, the researchers reported that the significance of embryo quality on the cumulative outcomes of IVF/ICSI increases with advancing age.
Posted in ART, Embryology, Fertility, ICSI, IVF, IVF Outcome, Infertility, PregnancyComments Off
26 October 2011
The pathogenesis of ovarian hyperstimulation syndrome (OHSS), although not completely elucidated, is associated with the increased vascular endothelial growth factor (VEGF)-mediated blood vessel permeability. A recent hypothesis on OHSS pathophysiology proposed the involvement of intra- and extracellular calcium ions in the onset and development of OHSS. This was independent of, but not contradictory to, the [...]
Posted in ART, Female Infertility, Fertility, IVF, IVF Outcome, Infertility, PCOS, PregnancyComments Off
19 October 2011
Pediatric oncologists have noted a significant increase in the number of childhood cancer survivors as a result of advancements in the medical field, which has raised the concerns of post-cancer reproductive health. Highlighting the presence of elevated FSH levels in one-third of young adult male childhood cancer survivors evaluated, a recent study has found FSH [...]
Posted in ART, Drugs, Endocrinology, Fertility, Fertility Preservation, Infertility, Male InfertilityComments Off
05 October 2011
Metformin is frequently used to help induce ovulatory menstrual cycles in polycystic ovary syndrome (PCOS) patients with oligomenorrhea. A recent multicenter, prospective, randomized, double-blind study reports that 12 weeks of metformin treatment prior to and during IVF/ICSI cycles, as opposed to placebo, substantially increases pregnancy and live birth rates in non-obese PCOS patients.
Posted in ART, Endocrinology, Female Infertility, Fertility, ICSI, IVF, IVF Outcome, Infertility, PCOS, PregnancyComments Off
05 October 2011
Touted as the first study to report the association between live birth rates (LBR) and number of eggs retrieved, a UK-based study has indicated that around 15 oocytes should be retrieved in an IVF cycle to maximize LBR. The study proposes the number of retrieved oocytes as a robust indicator of the IVF success rates.
Posted in ART, IVF, IVF Outcome, Infertility, News, PregnancyComments Off
Added on 11 February 2010
